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Selected Research Bibliography: Stroke

 


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  • Two times the Impairment reduction

    In a clinical study involving 56 stroke inpatients, the motor skills of the robot-treated group improved significantly more than the control group. An analysis of impairment measures showed that (1) interactive robotic therapy significantly reduced motor impairment of the treated limbs, and (2) added to conventional therapy, interactive robotic therapy provided about double the impairment reduction. [1]

  • Long lasting Improvement

    Patients from an early clinical study were recalled up to three years later, and it was found that patients who received robotic therapy sustained their improvement over those who did not. Moreover, subsequent follow-up studies re-examining these patients also confirmed the finding. [2] [3]

  • Improvement occurs even several years post onset or injury

    Patients who had suffered a single unilateral stroke one to five years earlier, and who were demonstrated to be in a “stable phase,” showed significant improvement after receiving robotic therapy three times a week for six weeks.
    These findings also suggest that such patients have a potential for further recovery, which conventional therapy has been unable to tap into. [4] [5] [6]


    References

    [1] (Volpe, B.T., Krebs, H.I., Hogan, N., Edelstein, O.L., Diels, C. and Aisen, M., A novel approach to stroke rehabilitation:robot-aided sensorimotor stimulation, Neurology, 54 (2000) 1938-44.)
    [2](Volpe, B.T., Krebs, H.I., Hogan, N., Edelsteinn, L., Diels, C.M. and Aisen, M.L., Robot training enhanced motor outcome in patients with stroke maintained over 3 years, Neurology, 53 (1999) 1874-6.)
    [3](Volpe, B.T., Krebs, H.I., Hogan, N.; "Is robot-aided sensorimotor training in stroke rehabilitation a realistic option?", Current Opinion in Neurology, Lippincott Williams & Wilkins, 14:745-752, 2001)
    [4] (Fasoli, S.D., Krebs, H.I., Stein, J., Frontera, W.R. and Hogan, N., Effects of Robotic Therapy on Motor Impairment and Recovery in Chronic Stroke, Archives of Physical Medicine and Rehabilitation ; 84(2003)477-82.)
    [5](Fasoli, S.E., Krebs, H.I., Stein, J., Frontera, W.R., Hughes, R., and Hogan, N., “Robotic Therapy for Chronic Motor Impairments after Stroke: Follow-Up Results,” Archives of Physical Medicine and Rehabilitation; 85:1106-1111, 2004.)
    [6](Ferraro, M., Palazzolo, J.J., Krol, J., Krebs, H.I., Hogan, N., Volpe, B.T., “Robot Aided Sensorimotor Arm Training Improves Outcome in Patients with Chronic Stroke,” Neurology, 61:1604-1607, 2003.)



 
 

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